Classic Comfort Food Chicken Casserole

Name: Classic Comfort Food Chicken Casserole
Prep time: 20 min
Cook time: 45 min
Total time: 1 h 5 min
Yield: 6 servings
Ingredients: 2 cups cooked chicken, shredded; 1 cup mixed vegetables (carrots, peas, corn); 1 can cream of chicken soup; 1/2 cup milk; 1 cup shredded cheddar cheese; 1 teaspoon garlic powder; 1 teaspoon onion powder; Salt and pepper to taste; 1 cup breadcrumbs; 2 tablespoons butter, melted

Highlighted under: Home Comfort Food Inspiration

I always look forward to whipping up my Classic Comfort Food Chicken Casserole, especially on those chilly evenings when I crave something hearty and soothing. This dish brings together tender chicken, creamy sauce, and a medley of vegetables, all baked to perfection under a comforting blanket of golden breadcrumbs. One bite transports me back to cozy family dinners, and I love how easy it is to prepare. It's the perfect dish to share with loved ones or to keep for those simple nights at home.

Created by

Rebecca Turner

Last updated on 2026-02-15T01:29:36.092Z

When crafting my Classic Comfort Food Chicken Casserole, I wanted to ensure each element contributed to a delightful experience. The creamy sauce is made from scratch, which adds a richness that store-bought options can’t match. I also find that using leftover roasted chicken not only saves time but also enhances the dish's flavor.

To elevate the casserole further, I like to sprinkle fresh herbs on top before serving. It adds a burst of freshness that perfectly balances the rich and creamy elements, making every bite simply irresistible. Trust me, your family will be asking for seconds!

Why You'll Love This Recipe
Comforting blend of flavors that feels like a warm hug
Versatile recipe that can accommodate various ingredients
Perfect for meal prep or feeding a crowd

Understanding Your Ingredients

The heart of the Classic Comfort Food Chicken Casserole lies in selecting high-quality ingredients. Using freshly cooked chicken, either boiled or roasted, gives the dish a more robust flavor compared to store-bought rotisserie chicken. When chopping your mixed vegetables, try to ensure uniform sizes for even cooking; frozen vegetables can be a time-saver but be sure to thaw and drain them to avoid excess moisture in your casserole.

Cream of chicken soup acts as the base for the creamy sauce, binding the chicken and vegetables together. If you prefer a healthier option or want to avoid preservatives, consider making a homemade version by combining equal parts milk and chicken stock with a thickening agent like cornstarch, seasoned to taste. This substitution will elevate the flavor profile of your casserole while keeping it wholesome.

Casserole Assembly and Techniques

When mixing your casserole, it's crucial to avoid overmixing; this ensures the chicken remains tender and the veggies retain some bite. A gentle fold is all you need, especially when incorporating the shredded cheddar cheese. For a more textured topping, consider adding a handful of crushed crackers or panko breadcrumbs to your standard breadcrumb mixture for extra crunch and flavor.

When transferring the mixture into your greased baking dish, take care to spread it evenly in the pan. This allows for uniform cooking and ensures that every bite has the same comforting flavors. The buttered breadcrumb topping is not just for aesthetics; it adds a rich, golden crust that contrasts beautifully with the creamy filling beneath.

Ingredients

Gather the following ingredients to prepare your casserole:

Ingredients

2 cups cooked chicken, shredded
1 cup mixed vegetables (carrots, peas, corn)
1 can cream of chicken soup
1/2 cup milk
1 cup shredded cheddar cheese
1 teaspoon garlic powder
1 teaspoon onion powder
Salt and pepper to taste
1 cup breadcrumbs
2 tablespoons butter, melted

Make sure all ingredients are prepared and measured before you start cooking!

Instructions

Follow these simple steps to make your casserole:

Preheat the Oven

Begin by preheating your oven to 350°F (175°C) to ensure it's hot and ready for baking.

Mix the Base

In a large bowl, combine the shredded chicken, mixed vegetables, cream of chicken soup, milk, garlic powder, onion powder, salt, and pepper. Stir until well mixed.

Add Cheese

Fold in half of the shredded cheddar cheese to the chicken mixture for added creaminess.

Transfer to Baking Dish

Pour the mixture into a greased 9x13-inch baking dish, spreading it evenly.

Prepare Topping

In a small bowl, combine breadcrumbs with melted butter and then sprinkle the remaining cheddar cheese over the top.

Bake

Bake the casserole in the preheated oven for 30-35 minutes or until the topping is golden brown and the casserole is bubbly.

Serve and Enjoy

Remove the casserole from the oven and let it rest for a few minutes before serving. Enjoy your comforting dish!

Now your delicious casserole is ready to be served!

Pro Tips

For an added crunch, consider mixing in some crispy fried onions into the breadcrumb topping before baking.

Make-Ahead and Storage Tips

This casserole shines as a make-ahead meal. You can assemble it a day in advance and keep it covered in the fridge until you're ready to bake. This not only saves time on busy evenings, but it also allows the flavors to meld for a richer taste. Alternatively, you can freeze it either before or after baking. If freezing unbaked, wrap the dish tightly with plastic wrap and aluminum foil to prevent freezer burn, and bake from frozen, adding an additional 10-15 minutes to the cooking time.

For leftovers, store any uneaten casserole in an airtight container in the refrigerator. It will keep well for up to three days. To reheat, cover the dish with foil to keep moisture in and warm it in a 350°F (175°C) oven for about 20-25 minutes. If you like your topping extra crispy, uncover it for the last 5-10 minutes.

Serving Suggestions and Variations

To elevate your casserole’s presentation, serve it garnished with fresh parsley or chives, adding a pop of color and an appealing herbal note that brightens each bite. Pair this comforting dish with a light side salad or steamed green beans to balance the richness, making for a satisfying and well-rounded meal that’s perfect for family gatherings.

Feel free to experiment with this recipe by incorporating other ingredients to suit your family’s preferences. Swap the mixed vegetables with broccoli, spinach, or even bell peppers for a twist. For a heartier dish, consider adding a layer of cooked rice or noodles in between the chicken and vegetable mix. The versatility of this casserole means you can create your own signature version while enjoying the classic comfort it brings.

Questions About Recipes

→ Can I use frozen vegetables?

Yes, frozen vegetables work well; just ensure they are thawed before mixing.

→ How can I make this recipe healthier?

You can substitute the cream of chicken soup with a low-fat version and use whole grain breadcrumbs.

→ Can I prepare this casserole in advance?

Absolutely! You can assemble it a day ahead and store it in the fridge until you're ready to bake.

→ What sides go well with this casserole?

A simple green salad or steamed vegetables would pair nicely with the casserole.